What is BPC 157 and How Can It Benefit You? Le Jolie Med Spa Oral Peptides Sublingual Peptides at Beautox Bar ORAL vs INJECTABLE BPC 157 Not all peptides work the same way and how you take BPC 157 matters. Here's the simple breakdown: Oral BPC 157 Best for gut health & People talk about BPC 157 like it's one thing. It isn't. Oral BPC 157 stays local. It survives digestion long enough to act on the GI mucosa, then clears before it reaches systemic circulation.