How GHK Peptide Works Signaling GHK acts as a switch for skin repair: Interacts with adenosine receptors reduces inflammation Activates MAPK ERK, PI3K Akt, TGF pathways Stimulates fibroblasts & keratinocytes boosts collagen, elastin Synergy of GHKCu and hyaluronic acid on collagen IV upregulation via fibroblast and exvivo skin tests Jiang 2023 Journal of Cosmetic Dermatology Wiley Online Library Before vs. after 3 months of GHK Cu peptide therapy smoother texture, more even tone, and skin that looks healthier overall. Small peptide, big difference of the effects of GHK on pulmonary fibrosis. GHK exerts anti fibrotic Download Scientific Diagram