9. Oxidative Stress, Green Tea, and Fatty Liver Disease Glutathione synthesis in the mouse liver supports lipid abundance through NRF2 repression Nature Communications Glutathione in liver diseases and hepatotoxicity. Semantic Scholar Hepatic Glutathione Synthesis: The Liver's Antioxidant Powerhouse Glutathione (GSH) is the most abundant intracellular antioxidantand the liver is its primary production site. Through a tightly regulated, ATP dependent pathway, hepatocytes