Frontiers Recent findings in the regulation of G6PD and its role in diseases Glucose 6 phosphate dehydrogenase (G6PD): Response of the human erythrocyte and another cells to the decrease in their activity Glucose 6 phosphate dehydrogenase deficiency Knowledge @ AMBOSS G6PD Deficiency Glucose 6 phosphate dehydrogenase deficiency X linked recessive disorder Leads to low NADPH, impairing glutathione regeneration RBCs are vulnerable to oxidative damage Pathophysiology: In G6PD deficiency: No