Dietary Antioxidants and Parkinson's Disease For every family touched by Parkinson's disease, this is research you deserve to know about. Glutathione levels in the substantia nigra, the brain region most devastated by Parkinson's ,are depleted by up Central nervous system uptake of intranasal glutathione in Parkinson's disease npj Parkinson's Disease Transient glutathione depletion in the substantia nigra compacta is associated with neuroinflammation in rats ScienceDirect