Peripherally Inserted Central Catheter (PICC) Dressing Management Clinical Guideline Central Line Dressing Change, , Central lines are at a high risk of serious infection. Proper central line care is a key to preventing these central line associated bloodstream infections called Central Venous Catheter Dressing Change Tray w Isopropyl Alcohol Swabsticks Preferred Medical Peripherally Inserted Central Catheter (PICC): Care Instructions